Study links ibuprofen to infertility

Ibuprofen Might Cause Male Infertility Study Shows			 0					By		Denis Bedoya

And now, new research shows that it can cause infertility, erectile dysfunction, muscle atrophy and fatigue in men.

Scientists analyzed the hormones and blood of a group of 31 healthy white men between 18 and 35 years old over the course of six weeks.

In addition to producing sperm, the testicles secrete testosterone, the primary male sex hormone.

Levels of luteinising hormone, which stimulates the testosterone production increased in the study participants but overall testosterone dropped. "Using a unique combination of a randomized, controlled clinical trial and ex vivo and in vitro approaches, we report a univocal depression of important aspects of testicular function, including testosterone production, after use of over-the-counter ibuprofen", the paper reads.

A new study links higher dosage of the over-the-counter painkiller ibuprofen to lower fertility in men.

Ibuprofen is one the most well-known pain medications in the West, taken by millions of people every day. Men were then divided - 14 in an ibuprofen group, 17 in a placebo group.


Compensated hypogonadism usually only affects the elderly or smokers, but taking ibuprofen increases a younger person's risk. This rose to a 23% decrease after 44 days.

All 3 drugs are considered anti-androgenic, meaning they disrupt male hormones.

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HollywoodLifers, did you know the negative effects of ibuprofen? The higher and longer the level of exposure, the researchers found, the more dramatic the impact.

No direct effect on fertility was shown, but the results of this initial study suggest that it warrants further investigation. The consistency of the results, however, as well as the earlier epidemiological results, suggest that there might really be an issue here.

According to the Proceedings of the National Academy of Sciences, prolonged and heavy use of the drug "alters human testicular physiology to produce a state of compensated hypogonadism". Professional athletes, however, do tend to take ibuprofen frequently, so this research could spark a serious look into the way those under physical strain treat their aches and pains.

The finding comes after repeated warnings from other researchers that ibuprofen can raise the risk of heart attacks in the general population and cause medical problems for pregnant women and their babies, including a more than doubling of the risk of miscarriage.

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