New device can heal with a single touch, study says

Groundbreaking skin patch the size of a penny can regrow organs, restore brain function, and heal wounds by injecting genetic code into the damaged area

By the second week, active blood vessels had formed, and by the third week, the legs of the mice were saved-with no other form of treatment.

In what is seen as a breakthrough in the field of regenerative medicine, Indian-origin researcher in the U.S. developed a technology that can fix organs, blood vessels and nerves by a single touch. "This process only takes less than a second and is non-invasive, and then you're off".

It is the first time scientists have reprogrammed cells within a live body.

Chandan Sen, director of the Center for Regenerative Medicine and Cell-Based Therapies, said that now, the technology not only works on skin cells, but can also fix other types of tissue.

Dr. Chandan Sen, director of Ohio State's Centre for Regenerative Medicine and Cell Based Therapies said of the development: "This is hard to imagine, but it is achievable, successfully working about 98% of the time".

Thus far, researchers say that the technique has worked 98 percent of the time.

Lead author Daniel Gallego-Perez says the new technology comprises two elements: the nanotech chip created to introduce reprogrammed DNA into existing adult cells; and a "specific biological cargo" that induces the cells to change from one type to another.

Researchers were able to reprogram skin cells to become vascular cells in severely injured legs that lacked blood flow. The second is the design of the particular biological cargo for cell conversion.

Apparently, an adult cell can be converted from one type to another after the nanochip has delivered the cargo. By doing so, the device turn the skin cells into other cell types which are required to treat the patient's disease. Through this process, the DNA will be converted to the specific building block cells of the damaged body part.

Researchers said the technology itself is small and portable, allowing it to be used outside of a doctor's office or lab.

"The concept is very simple". In my lab, we have ongoing research trying to understand the mechanism and do even better. "So this is the beginning, more to come".

Since the method uses a patient's own cells and does not depend upon medication, the Researchers anticipate it to be approved for human trials by the end of the year.

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